Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology

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Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology

Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology


Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology


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Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology

Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography.  Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.

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Product details

Hardcover: 800 pages

Publisher: Garland Science; 1 edition (October 20, 2009)

Language: English

ISBN-10: 0815340818

ISBN-13: 978-0815340812

Product Dimensions:

8.2 x 1.5 x 10.8 inches

Shipping Weight: 4.3 pounds (View shipping rates and policies)

Average Customer Review:

4.9 out of 5 stars

13 customer reviews

Amazon Best Sellers Rank:

#219,923 in Books (See Top 100 in Books)

This is one of the best crystallography books you can buy. It actually goes into some practical detail contrasted with most books that are 90% theory and just skim over practical stuff. Lots of useful pictures to try to explain the very abstract concepts involved.Also, I bought it from the Amazon seller Bookera (based in India) for $50 cheaper than buying it directly from Amazon for a brand new, still sealed hardcover book. I had it expedited for $7 and it arrived in 4 days. There was some very minor damage to the cover, I imagine from the knot being too tight, but it's otherwise in perfect condition.

Yet I have to admit I am not yet completely done with it. The author has wonderful understanding of the subject and he presents it clearly for a biochemist, albeit non- crystallographer.

I had been looking for a good book on crystallography of proteins for a long time. I had looked into Jan Drenth's book - but found it to be too superficial and at best, only a run through guide for last minute preparation for exams. This book is definitely a great one for those who want to understand protein crystallography real well - adequate and clear explanations, quite detailed and thorough and definitely written for a very broad audience. My only complaint is that it is not very heavy on the fundamentals of X-ray diffraction and phase problem analysis. While descriptions might seem to be adequate initially, the math is quite lacking. But then again, I've not yet found good biomolecular crystallography books which explain the physics of the problem any better. I had to opt for a mineral/small molecule crystallography book (by Giacovazzo Fundamentals of Crystallography) for frequent reference and when used together - they seemed to very good and rigorous. Nonetheless I would strongly reccommend this book - probably its the best in the market (related to biomolecules).

lots of figures, images to help you understand, many chapters on practical use, very practical

Worth the money for someone doing X-ray crystallography

Every structural biology student should get it.

I have nothing to say about this book except that it is just PERFECT! I love the structure of the book, the way it is written in order to make it easy to read even for beginners (like me) in macromolecular crystallography.I definitely give it 5 stars!

Great book for better understanding of crystallography. If read in conjunction with Crystallography Made Crystal Clear, you will understand crystallography very well.

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Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology


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